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Newfound protein may prevent viral infection, herpes-induced cancer
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A human protein has been identified that could prevent cancer by restricting a type of herpes virus from replicating. Most people are infected by several herpes viruses by the time they reach adulthood. Learning how to stop herpes virus 8 from spreading may hint to how to prevent the other seven types, such as the […]

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Hush little virus, don't say a word: How scientists investigate sleeping viruses
www.sciencedaily.com

Four in five adults are infected with herpes simplex virus, say researchers, but most don’t show symptoms like cold sores because the virus infection is ‘latent’ — sleeping — within the nervous system. While many virus researchers are interested in understanding what causes these sleeping viruses to wake up, or reactivate, scientists are now trying […]

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Exploring how herpes simplex virus changes when passed between family members
www.sciencedaily.com

A new study offers a rare glimpse into the genetics of a herpes simplex virus transmission event — information that may prove useful in future development of therapeutics and vaccines. The study reveals nearly perfect genetic transmission of the virus from a father to his son and lays the foundation for future studies exploring the […]

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Chimera viruses can help the fight against lymphomas
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Researchers have created a chimera virus that allows the study of molecules to treat cancers caused by human herpes virus infection in mice models of disease.

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Epigenetic drugs show promise as antivirals
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Some epigenetic pharmaceuticals have the potential to be used as broad spectrum antivirals, according to a new study. The study demonstrated that histone methyltransferases EZH2/1 inhibitors, which are being used in cancer clinical trials, have activity against a variety of viruses, including herpes simplex virus (HSV).

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Unknown virus discovered in 'throwaway' DNA
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A chance discovery has opened up a new method of finding unknown viruses. Researchers have revealed that Next-Generation Sequencing and its associated online DNA databases could be used in the field of viral discovery. They have developed algorithms that detect DNA from viruses that happen to be in fish blood or tissue samples, and could […]

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Master molecule behind corneal inflammation identified
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An enzyme present in the cornea that becomes dramatically upregulated and triggers inflammation during and even after a herpes virus infection has cleared has now been identified by researchers.

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Hidden herpes virus may play key role in MS, other brain disorders
www.sciencedaily.com

The ubiquitous human herpesvirus 6 may play a critical role in impeding the brain’s ability to repair itself in diseases like multiple sclerosis. These findings may help explain the differences in severity in symptoms that many people with the disease experience.

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Mothers with history of herpes can protect their offspring from neurological infection
www.sciencedaily.com

Pregnant women with a previous history of herpes simplex virus type 1 (HSV-1) infection maintain active antibodies against the virus, and researchers have found that this protection can pass to the nervous systems of their offspring.

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Understanding of herpesvirus infection advanced by new research
www.sciencedaily.com

Herpes simplex virus (HSV) infections last a lifetime. Once a person has been infected, the virus can remain dormant (latent) for years before periodically reactivating to cause recurrent disease. This poorly understood cycle has frustrated scientists for years. Now, scientists have identified a set of protein complexes that are recruited to viral genes and stimulate […]

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