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New neuron-like cells allow investigation into synthesis of vital cellular components
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A new method to create synthetic neurons allows researchers to investigate how the human brain makes metabolic building blocks essential for the survival of all living organisms. A new study describes a core enzyme involved in the synthesis of these building blocks, called purines, and how the enzyme might change during infection by herpes simplex […]

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Structure of herpes virus linked to Kaposi's sarcoma
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Scientists have shown in the laboratory that an inhibitor can be developed to break down the herpes virus. Kaposi’s sarcoma-associated herpes virus, or KSHV, is one of two viruses known to cause cancer in humans.

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Designer nanoparticles destroy a broad array of viruses
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Researchers have designed new anti-viral nanoparticles that bind to a range of viruses. Unlike other broad-spectrum antivirals, the new nanoparticles destroy viruses.

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Newfound protein may prevent viral infection, herpes-induced cancer
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A human protein has been identified that could prevent cancer by restricting a type of herpes virus from replicating. Most people are infected by several herpes viruses by the time they reach adulthood. Learning how to stop herpes virus 8 from spreading may hint to how to prevent the other seven types, such as the […]

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Hush little virus, don't say a word: How scientists investigate sleeping viruses
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Four in five adults are infected with herpes simplex virus, say researchers, but most don’t show symptoms like cold sores because the virus infection is ‘latent’ — sleeping — within the nervous system. While many virus researchers are interested in understanding what causes these sleeping viruses to wake up, or reactivate, scientists are now trying […]

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Exploring how herpes simplex virus changes when passed between family members
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A new study offers a rare glimpse into the genetics of a herpes simplex virus transmission event — information that may prove useful in future development of therapeutics and vaccines. The study reveals nearly perfect genetic transmission of the virus from a father to his son and lays the foundation for future studies exploring the […]

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Chimera viruses can help the fight against lymphomas
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Researchers have created a chimera virus that allows the study of molecules to treat cancers caused by human herpes virus infection in mice models of disease.

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Epigenetic drugs show promise as antivirals
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Some epigenetic pharmaceuticals have the potential to be used as broad spectrum antivirals, according to a new study. The study demonstrated that histone methyltransferases EZH2/1 inhibitors, which are being used in cancer clinical trials, have activity against a variety of viruses, including herpes simplex virus (HSV).

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Unknown virus discovered in 'throwaway' DNA
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A chance discovery has opened up a new method of finding unknown viruses. Researchers have revealed that Next-Generation Sequencing and its associated online DNA databases could be used in the field of viral discovery. They have developed algorithms that detect DNA from viruses that happen to be in fish blood or tissue samples, and could […]

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Master molecule behind corneal inflammation identified
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An enzyme present in the cornea that becomes dramatically upregulated and triggers inflammation during and even after a herpes virus infection has cleared has now been identified by researchers.

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