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Epigenetic drugs show promise as antivirals
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Some epigenetic pharmaceuticals have the potential to be used as broad spectrum antivirals, according to a new study. The study demonstrated that histone methyltransferases EZH2/1 inhibitors, which are being used in cancer clinical trials, have activity against a variety of viruses, including herpes simplex virus (HSV).

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Unknown virus discovered in 'throwaway' DNA
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A chance discovery has opened up a new method of finding unknown viruses. Researchers have revealed that Next-Generation Sequencing and its associated online DNA databases could be used in the field of viral discovery. They have developed algorithms that detect DNA from viruses that happen to be in fish blood or tissue samples, and could […]

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Master molecule behind corneal inflammation identified
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An enzyme present in the cornea that becomes dramatically upregulated and triggers inflammation during and even after a herpes virus infection has cleared has now been identified by researchers.

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Hidden herpes virus may play key role in MS, other brain disorders
www.sciencedaily.com

The ubiquitous human herpesvirus 6 may play a critical role in impeding the brain’s ability to repair itself in diseases like multiple sclerosis. These findings may help explain the differences in severity in symptoms that many people with the disease experience.

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Mothers with history of herpes can protect their offspring from neurological infection
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Pregnant women with a previous history of herpes simplex virus type 1 (HSV-1) infection maintain active antibodies against the virus, and researchers have found that this protection can pass to the nervous systems of their offspring.

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Understanding of herpesvirus infection advanced by new research
www.sciencedaily.com

Herpes simplex virus (HSV) infections last a lifetime. Once a person has been infected, the virus can remain dormant (latent) for years before periodically reactivating to cause recurrent disease. This poorly understood cycle has frustrated scientists for years. Now, scientists have identified a set of protein complexes that are recruited to viral genes and stimulate […]

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New research comes to terms with old ideas about canker sores
www.sciencedaily.com

A burning pain sensation — and treatments that do not work. This is what daily life is like for many of those who suffer from recurrent aphthous stomatitis. Research now sheds new light on the reasons behind this condition found in the mouth.

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Autism risk linked to herpes infection during pregnancy
www.sciencedaily.com

Women actively infected with genital herpes during early pregnancy had twice the odds of giving birth to a child later diagnosed with autism spectrum disorder (ASD), according to a study.

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New genital herpes vaccine candidate provides powerful protection in preclinical tests
www.sciencedaily.com

Approximately 500 million people around the world are infected with the genital herpes virus known as herpes simplex virus 2 (HSV2). A vaccine that could bring an end to this global pandemic is needed desperately, yet no candidate vaccine has ever performed well in clinical trials. Now scientists have shown that a new type of […]

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Using herpes drugs to slow down Alzheimer's disease could become reality
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The first clinical study to investigate if herpes virus drugs can have an effect on fundamental Alzheimer’s disease processes has been launched. The research group has previously demonstrated a correlation between herpes virus infection and an increased risk of Alzheimer’s disease.

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