Four in five adults are infected with herpes simplex virus, say researchers, but most don’t show symptoms like cold sores because the virus infection is ‘latent’ — sleeping — within the nervous system. While many virus researchers are interested in understanding what causes these sleeping viruses to wake up, or reactivate, scientists are now trying […]
A new study offers a rare glimpse into the genetics of a herpes simplex virus transmission event — information that may prove useful in future development of therapeutics and vaccines. The study reveals nearly perfect genetic transmission of the virus from a father to his son and lays the foundation for future studies exploring the […]
Researchers have created a chimera virus that allows the study of molecules to treat cancers caused by human herpes virus infection in mice models of disease.
Some epigenetic pharmaceuticals have the potential to be used as broad spectrum antivirals, according to a new study. The study demonstrated that histone methyltransferases EZH2/1 inhibitors, which are being used in cancer clinical trials, have activity against a variety of viruses, including herpes simplex virus (HSV).
A chance discovery has opened up a new method of finding unknown viruses. Researchers have revealed that Next-Generation Sequencing and its associated online DNA databases could be used in the field of viral discovery. They have developed algorithms that detect DNA from viruses that happen to be in fish blood or tissue samples, and could […]
An enzyme present in the cornea that becomes dramatically upregulated and triggers inflammation during and even after a herpes virus infection has cleared has now been identified by researchers.
The ubiquitous human herpesvirus 6 may play a critical role in impeding the brain’s ability to repair itself in diseases like multiple sclerosis. These findings may help explain the differences in severity in symptoms that many people with the disease experience.
Pregnant women with a previous history of herpes simplex virus type 1 (HSV-1) infection maintain active antibodies against the virus, and researchers have found that this protection can pass to the nervous systems of their offspring.
Herpes simplex virus (HSV) infections last a lifetime. Once a person has been infected, the virus can remain dormant (latent) for years before periodically reactivating to cause recurrent disease. This poorly understood cycle has frustrated scientists for years. Now, scientists have identified a set of protein complexes that are recruited to viral genes and stimulate […]
A burning pain sensation — and treatments that do not work. This is what daily life is like for many of those who suffer from recurrent aphthous stomatitis. Research now sheds new light on the reasons behind this condition found in the mouth.