Herpes Virus

A novel therapy for genital herpes engages immune cells to provide significant patient benefits
www.sciencedaily.com

A phase II clinical trial demonstrated that a new type of treatment for genital herpes, an immunotherapy called GEN-003, may reduce the activity of the virus and the number of days with recurrent herpes. This effect of treatment, given by a series of three injections, appears to last for up to at least one year.

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Constipated? Study finds surprising cause
www.sciencedaily.com

A new study has shown a surprising link between constipation and herpes infection. The finding advances the science on herpes, and could help patients with chronic gastrointestinal diseases with no clear cause.

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Making virus sensors cheap and simple: New method detects single viruses in urine
www.sciencedaily.com

Scientists have developed a new method to rapidly detect a single virus in urine. While the technique presently works on just one virus, scientists say it could be adapted to detect a range of viruses that plague humans, including Ebola, Zika and HIV.

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How antibodies access neurons to fight infection
www.sciencedaily.com

Scientists have solved a puzzle of the immune system — how antibodies enter the nervous system to control viral infections. Their finding may have implications for the prevention and treatment of a range of conditions, including herpes and Guillain-Barre syndrome, which has been linked to the Zika virus.

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Nanoparticles hold promise as double-edged sword against genital herpes
www.sciencedaily.com

An effective vaccine against the virus that causes genital herpes has evaded researchers for decades. But now, researchers from the University of Illinois at Chicago working with scientists from Germany have shown that zinc-oxide nanoparticles shaped like jacks can prevent the virus from entering cells, and help natural immunity to develop.

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Scientists reveal new target for anti-lymphangiogenesis drugs
www.sciencedaily.com

In an emerging field of research, a study reveals a mechanism in the regulation of lymphangiogenesis. Scientists identified a new target for drug treatment to prevent conditions caused by lymphangiogenesis, which include some blinding eye diseases, organ transplant rejection, and cancer metastasis.

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Stress wakes up sleeping herpes viruses – but how?
www.sciencedaily.com

Hiding their DNA genome inside the nucleus of the infected cells, the herpes viruses establish a lifelong infection in humans, and they are known to reactivate in response to different kinds of stress. The researchers have now found an important link between cellular stress responses, cell cycle regulation and virus reactivation.

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'Key' to recognizing, immunizing herpes/common cold
www.sciencedaily.com

Prior to this study, it was known that interferon regulatory factor-3 (IRF-3), a protein coding gene, contributed to a first line of defense against viral infection by triggering antiviral activity. However the activation of IRF-3 following infection was not fully understood. The study found that an interaction with the protein S6K1 and the signaling adaptor […]

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First case of acute myelitis in a patient infected with Zika virus
www.sciencedaily.com

A first case of acute myelitis following infection with Zika virus has been reported for the first time. A young patient in the acute phase of an infection by Zika virus presented motor deficiency in the four limbs, associated with very intense pain and acute urinary retention.

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Increased demand for 'vaginal seeding' from new parents, despite lack of evidence
feeds.sciencedaily.com

Doctors are seeing a rise in the number of parents requesting so-called ‘vaginal seeding’ for babies born by cesarean section, according to a new article. The practice, which is also known as microbirthing, involves taking a swab from the mother’s vagina and wiping this over the baby’s mouth, eyes, face and skin shortly after birth […]

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