Herpes Virus

'Key' to recognizing, immunizing herpes/common cold
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Prior to this study, it was known that interferon regulatory factor-3 (IRF-3), a protein coding gene, contributed to a first line of defense against viral infection by triggering antiviral activity. However the activation of IRF-3 following infection was not fully understood. The study found that an interaction with the protein S6K1 and the signaling adaptor […]

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First case of acute myelitis in a patient infected with Zika virus
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A first case of acute myelitis following infection with Zika virus has been reported for the first time. A young patient in the acute phase of an infection by Zika virus presented motor deficiency in the four limbs, associated with very intense pain and acute urinary retention.

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Increased demand for 'vaginal seeding' from new parents, despite lack of evidence
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Doctors are seeing a rise in the number of parents requesting so-called ‘vaginal seeding’ for babies born by cesarean section, according to a new article. The practice, which is also known as microbirthing, involves taking a swab from the mother’s vagina and wiping this over the baby’s mouth, eyes, face and skin shortly after birth […]

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Stress wakes up sleeping herpes viruses – but how?
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Hiding their DNA genome inside the nucleus of the infected cells, the herpes viruses establish a lifelong infection in humans, and they are known to reactivate in response to different kinds of stress. The researchers have now found an important link between cellular stress responses, cell cycle regulation and virus reactivation.

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Zika virus can cross placental barrier, but link with microcephaly remains unclear, new evidence suggests
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Zika virus has been detected in the amniotic fluid of two pregnant women whose fetuses had been diagnosed with microcephaly, according to a study. The report suggests that Zika virus can cross the placental barrier, but does not prove that the virus causes microcephaly, as more research is needed to understand the link.

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Cold sores increase risk of dementia, research suggests
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Infection with herpes simplex virus increases the risk of Alzheimer’s disease, researchers claim. “Our results clearly show that there is a link between infections of herpes simplex virus and the risk of developing Alzheimer’s disease. This also means that we have new opportunities to develop treatment forms to stop the disease,” says one of the […]

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Model helps decide drug dose for clinical testing
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A mathematical model may offer a valuable tool for selecting the proper dose of antiviral drugs for further testing in clinical trials.

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How herpes virus tricks the immune system
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Scientists have captured atomic images of the virus that causes cold sores in action. Structural details reveal that the virus inserts itself into another protein, jamming an important immune system pathway that normally allows immune cells to recognize and destroy foreign invaders.

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Herpes zoster is linked to increased rates of both stroke and myocardial infarction
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Herpes zoster (also called ‘shingles’) is linked to a transient increased risk of stroke and myocardial infarction in the months following initial zoster diagnosis, according to a new study.

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Shingles increases short-term risk of stroke in older adults
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A new study determined that adults 50 and older are at a 50% increased risk for stroke for 90 days following a shingles episode.

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